A one-owner PLLC is disregarded by default, so practice profit goes on Schedule C and is subject to self-employment tax. With two or more owners it is a partnership filing Form 1065. Either can elect corporate treatment, and an eligible LLC that files Form 2553 does not also need Form 8832. The election is due within 2 months and 15 days of the start of the tax year it takes effect, or during the prior year.
A professional corporation starts in a different place. It is incorporated under state law, so it is a corporation for federal tax purposes and files Form 1120 at the flat 21% rate unless it makes an S election. Profit paid out as dividends is taxed again to the owner.
Illustrative example, not a client result: a single physician with no other wages has $400,000 of profit in a PLLC. On Schedule C, 2026 SE tax including the 0.9% Additional Medicare Tax is about $35,115. With an S election and a hypothetical $230,000 salary, combined payroll tax is about $29,818, a difference of about $5,297. Above the $184,500 wage base the gain comes mostly from Medicare taxes, so payroll cost, a second return, and lower plan compensation can use up a good part of it. Salary must be supportable as reasonable compensation.
You can test your own numbers with our S corp tax calculator. It is an educational estimate, not a recommendation for your practice.